RBM3 promotes neurogenesis in a niche-dependent manner via IMP2-IGF2 signaling pathway after hypoxic-ischemic brain injury

Hypoxic ischemia (HI) is an acute brain threat across all age groups. Therapeutic hypothermia ameliorates resulting injury in neonates but its side effects prevent routine use in adults. Hypothermia up-regulates a small protein subset that includes RNA-binding motif protein 3 (RBM3), which is neurop...

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Vydáno v:Nat Commun
Hlavní autoři: Zhu, Xinzhou, Yan, Jingyi, Bregere, Catherine, Zelmer, Andrea, Goerne, Tessa, Kapfhammer, Josef P., Guzman, Raphael, Wellmann, Sven
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726629/
https://ncbi.nlm.nih.gov/pubmed/31484925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11870-x
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