Systems-level quantitative analysis of inter-organ metabolite exchange in pigs

Mammalian organs continually exchange metabolites via circulation, but systems-level analysis of this shuttling process is lacking. Here we compared, in fasted pigs, metabolite concentrations in arterial blood versus draining venous blood from 11 organs. Greater than 90% of metabolites showed arteri...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Jang, Cholsoon, Hui, Sheng, Zeng, Xianfeng, Cowan, Alexis J., Wang, Lin, Chen, Li, Morscher, Raphael J., Reyes, Jorge, Frezza, Christian, Hwang, Ho Young, Imai, Akito, Saito, Yoshiaki, Okamoto, Keitaro, Vaspoli, Christine, Kasprenski, Loewe, Zsido, Gerald A., Gorman, Joseph H., Gorman, Robert C., Rabinowitz, Joshua D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726553/
https://ncbi.nlm.nih.gov/pubmed/31257152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.06.002
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