Astrocyte morphogenesis is dependent on BDNF signaling via astrocytic TrkB.T1

Brain-derived neurotrophic factor (BDNF) is a critical growth factor involved in the maturation of the CNS, including neuronal morphology and synapse refinement. Herein, we demonstrate astrocytes express high levels of BDNF’s receptor, TrkB (in the top 20 of protein-coding transcripts), with nearly...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Holt, Leanne M, Hernandez, Raymundo D, Pacheco, Natasha L, Torres Ceja, Beatriz, Hossain, Muhannah, Olsen, Michelle L
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726422/
https://ncbi.nlm.nih.gov/pubmed/31433295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44667
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