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The kinetic origins of the restriction point in the mammalian cell cycle

Abstract. A detailed model mechanism for the G1/S transition in the mammalian cell cycle is presented and analysed by computer simulation to investigate whether the kinetic origins of the restriction point (R‐point) can be identified. The R‐point occurs in mid‐to‐late G1 phase and marks the transiti...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Aguda, B. D., Tang, Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Ltd 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726334/
https://ncbi.nlm.nih.gov/pubmed/10619492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2184.1999.3250321.x
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