Detection of MYD88 L265P mutation by next-generation deep sequencing in peripheral blood mononuclear cells of Waldenström’s macroglobulinemia and IgM monoclonal gammopathy of undetermined significance

We investigated the feasibility of using next-generation sequencing (NGS) technique using molecular barcoding technology to detect MYD88 L265P mutation in unselected peripheral blood mononuclear cells (PBMCs) in 52 patients with Waldenström’s macroglobulinemia [1] and 21 patients with IgM-monoclonal...

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Publicat a:PLoS One
Autors principals: Nakamura, Ayako, Ohwada, Chikako, Takeuchi, Masahiro, Takeda, Yusuke, Tsukamoto, Shokichi, Mimura, Naoya, Nagisa, Oshima-Hasegawa, Sugita, Yasumasa, Tanaka, Hiroaki, Wakita, Hisashi, Aotsuka, Nobuyuki, Matsue, Kosei, Yokote, Koutaro, Ohara, Osamu, Nakaseko, Chiaki, Sakaida, Emiko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726192/
https://ncbi.nlm.nih.gov/pubmed/31483817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221941
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