Persistent Phosphorylation by Protein Kinase Mζ Maintains Late-Phase Long-Term Potentiation

Protein kinase Mζ (PKMζ), an autonomously active atypical PKC isoform, is both necessary and sufficient for enhanced synaptic transmission during long-term potentiation (LTP) maintenance. LTP, however, evolves through several temporal phases, which may be mediated by distinct molecular mechanisms of...

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Publicado en:J Neurosci
Autores principales: Serrano, Peter, Yao, Yudong, Sacktor, Todd Charlton
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2005
Materias:
Brief Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726070/
https://ncbi.nlm.nih.gov/pubmed/15728837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5132-04.2005
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