Presenilin-1-Dependent Transcriptome Changes

Familial forms of Alzheimer's disease (FADs) are caused by the expression of mutant presenilin 1 (PS1) or presenilin 2. Using DNA microarrays, we explored the brain transcription profiles of mice with conditional knock-out of PS1 (cKO PS1) in the forebrain. In parallel, we performed a transcrip...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Mirnics, Károly, Korade, Zeljka, Arion, Dominique, Lazarov, Orly, Unger, Travis, Macioce, Melissa, Sabatini, Michael, Terrano, David, Douglass, Katherine C., Schor, Nina F., Sisodia, Sangram S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726008/
https://ncbi.nlm.nih.gov/pubmed/15703411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4145-04.2005
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