Overexpression of GD1a Ganglioside Sensitizes Motor Nerve Terminals to Anti-GD1a Antibody-Mediated Injury in a Model of Acute Motor Axonal Neuropathy

Anti-GD1a ganglioside antibodies (Abs) are the serological hallmark of the acute motor axonal form of the post-infectious paralysis, Guillain-Barré syndrome. Development of a disease model in mice has been impeded by the weak immunogenicity of gangliosides and the apparent resistance of GD1a-contain...

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Pubblicato in:J Neurosci
Autori principali: Goodfellow, John A., Bowes, Tyrone, Sheikh, Kazim, Odaka, Masaaki, Halstead, Susan K., Humphreys, Peter D., Wagner, Eric R., Yuki, Nobuhiro, Furukawa, Koichi, Furukawa, Keiko, Plomp, Jaap J., Willison, Hugh J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2005
Soggetti:
Neurobiology of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725939/
https://ncbi.nlm.nih.gov/pubmed/15716397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4279-04.2005
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