Downstream Regulatory Element Antagonist Modulator Regulates Ca(2+) Homeostasis and Viability in Cerebellar Neurons

The Na(+)/Ca(2+) exchangers NCX1, NCX2, and NCX3 are vital for the control of cellular Ca(2+) homeostasis. Here, we show that a doublet of downstream regulatory element sites in the promoter of the NCX3 gene mediates transcriptional repression of NCX3 by the Ca(2+)-modulated transcriptional represso...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Gomez-Villafuertes, Rosa, Torres, Begoña, Barrio, Jorge, Savignac, Magali, Gabellini, Nadia, Rizzato, Federico, Pintado, Belen, Gutierrez-Adan, Alfonso, Mellström, Britt, Carafoli, Ernesto, Naranjo, Jose R.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2005
Sujets:
Cellular/Molecular
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725879/
https://ncbi.nlm.nih.gov/pubmed/16306395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3912-05.2005
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