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Cholinergic Deafferentation of the Entorhinal Cortex in Rats Impairs Encoding of Novel But Not Familiar Stimuli in a Delayed Nonmatch-to-Sample Task

Acetylcholine may regulate working memory for novel stimuli by activating intrinsic mechanisms for sustained spiking in entorhinal cortical neurons, which have been demonstrated in slice preparations of the entorhinal cortex. Computational modeling demonstrates that loss of the cholinergic activatio...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: McGaughy, Jill, Koene, Randal A., Eichenbaum, Howard, Hasselmo, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725783/
https://ncbi.nlm.nih.gov/pubmed/16267235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2386-05.2005
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