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NMDA/AMPA Ratio Impacts State Transitions and Entrainment to Oscillations in a Computational Model of the Nucleus Accumbens Medium Spiny Projection Neuron

We describe a computational model of the principal cell in the nucleus accumbens (NAcb), the medium spiny projection (MSP) neuron. The model neuron, constructed in NEURON, includes all of the known ionic currents in these cells and receives synaptic input from simulated spike trains via NMDA, AMPA,...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Wolf, John A., Moyer, Jason T., Lazarewicz, Maciej T., Contreras, Diego, Benoit-Marand, Marianne, O'Donnell, Patricio, Finkel, Leif H.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725747/
https://ncbi.nlm.nih.gov/pubmed/16207867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2220-05.2005
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