The Translation Repressor 4E-BP2 Is Critical for eIF4F Complex Formation, Synaptic Plasticity, and Memory in the Hippocampus

Long-lasting synaptic plasticity and memory requires mRNA translation, yet little is known as to how this process is regulated. To explore the role that the translation repressor 4E-BP2 plays in hippocampal long-term potentiation (LTP) and learning and memory, we examined 4E-BP2 knock-out mice. Inte...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Banko, Jessica L., Poulin, Francis, Hou, Lingfei, DeMaria, Christine T., Sonenberg, Nahum, Klann, Eric
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2005
Sujets:
Cellular/Molecular
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725736/
https://ncbi.nlm.nih.gov/pubmed/16237163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2423-05.2005
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