Inositol 1,4,5-Trisphosphate-Dependent Ca(2+) Threshold Dynamics Detect Spike Timing in Cerebellar Purkinje Cells

Large Ca(2+) signals essential for cerebellar long-term depression (LTD) at parallel fiber (PF)-Purkinje cell synapses are known to be induced when PF activation precedes climbing fiber (CF) activation by 50-200 ms, consistent with cerebellar learning theories. However, large Ca(2+) signals and/or L...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Doi, Tomokazu, Kuroda, Shinya, Michikawa, Takayuki, Kawato, Mitsuo
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2005
Subjects:
Behavioral/Systems/Cognitive
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725626/
https://ncbi.nlm.nih.gov/pubmed/15673676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2727-04.2005
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