Overexpression of PrP(C) by Adenovirus-Mediated Gene Targeting Reduces Ischemic Injury in a Stroke Rat Model

Prion diseases are induced by pathologically misfolded prion protein (PrP(Sc)), which recruit normal sialoglycoprotein PrP(C) by a template-directed process. In this study, we investigated the expression of PrP(C) in a rat model of cerebral ischemia to more fully understand its physiological role. I...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Shyu, Woei-Cherng, Lin, Shinn-Zong, Chiang, Ming-Fu, Ding, Dah-Ching, Li, Kuo-Wei, Chen, Shih-Fen, Yang, Hui-I, Li, Hung
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725592/
https://ncbi.nlm.nih.gov/pubmed/16192387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1115-05.2005
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