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Monoamine Oxidase Inhibition Dramatically Increases the Motivation to Self-Administer Nicotine in Rats

Nicotine is the major neuroactive compound of tobacco, which has, by itself, weak reinforcing properties. It is known that levels of the enzymes monoamine oxidase A (MAO-A) and MAO-B are reduced in the platelets and brains of smokers and that substances, other than nicotine, present in tobacco smoke...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Guillem, Karine, Vouillac, Caroline, Azar, Marc R., Parsons, Loren H., Koob, George F., Cador, Martine, Stinus, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725504/
https://ncbi.nlm.nih.gov/pubmed/16177026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2139-05.2005
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