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3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors Attenuate β-Amyloid-Induced Microglial Inflammatory Responses

Alzheimer's disease (AD) is characterized by extracellular deposits of fibrillar β-amyloid (Aβ) in the brain, a fulminant microglial-mediated inflammatory reaction, and neuronal death. The use of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) is associated with a reduced r...

詳細記述

保存先:
書誌詳細
出版年:J Neurosci
主要な著者: Cordle, Andrew, Landreth, Gary
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725473/
https://ncbi.nlm.nih.gov/pubmed/15647473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2544-04.2005
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