Synaptically Driven Endocannabinoid Release Requires Ca(2)+-Assisted Metabotropic Glutamate Receptor Subtype 1 to Phospholipase C β4 Signaling Cascade in the Cerebellum

Endocannabinoids mediate retrograde signaling and modulate synaptic transmission in various regions of the CNS. Depolarization-induced elevation of intracellular Ca(2+) concentration causes endocannabinoid-mediated suppression of excitatory/inhibitory synaptic transmission. Activation of G(q/11)-cou...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Maejima, Takashi, Oka, Saori, Hashimotodani, Yuki, Ohno-Shosaku, Takako, Aiba, Atsu, Wu, Dianqing, Waku, Keizo, Sugiura, Takayuki, Kano, Masanobu
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2005
Materias:
Cellular/Molecular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725357/
https://ncbi.nlm.nih.gov/pubmed/16033892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0945-05.2005
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