Blocking Caspase Activity Prevents Transsynaptic Neuronal Apoptosis and the Loss of Inhibition in Lamina II of the Dorsal Horn after Peripheral Nerve Injury

We show that transsynaptic apoptosis is induced in the superficial dorsal horn (laminas I-III) of the spinal cord by three distinct partial peripheral nerve lesions: spared nerve injury, chronic constriction, and spinal nerve ligation. Ongoing activity in primary afferents of the injured nerve and g...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Scholz, Joachim, Broom, Daniel C., Youn, Dong-Ho, Mills, Charles D., Kohno, Tatsuro, Suter, Marc R., Moore, Kimberly A., Decosterd, Isabelle, Coggeshall, Richard E., Woolf, Clifford J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Behavioral/Systems/Cognitive
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725303/
https://ncbi.nlm.nih.gov/pubmed/16093381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1526-05.2005
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