Cholinergic Suppression of KCNQ Channel Currents Enhances Excitability of Striatal Medium Spiny Neurons

In response to glutamatergic synaptic drive, striatal medium spiny neurons in vivo transition to a depolarized “up state” near spike threshold. In the up state, medium spiny neurons either depolarize enough to spike or remain below spike threshold and are silent before returning to the hyperpolarize...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Shen, Weixing, Hamilton, Susan E., Nathanson, Neil M., Surmeier, D. James
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2005
Subjects:
Cellular/Molecular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725301/
https://ncbi.nlm.nih.gov/pubmed/16093396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1381-05.2005
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