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Trafficking of GABA(A) Receptors, Loss of Inhibition, and a Mechanism for Pharmacoresistance in Status Epilepticus
During status epilepticus (SE), GABAergic mechanisms fail and seizures become self-sustaining and pharmacoresistant. During lithiumpilocarpine-induced SE, our studies of postsynaptic GABA(A) receptors in dentate gyrus granule cells show a reduction in the amplitude of miniature IPSCs (mIPSCs). Anato...
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| Udgivet i: | J Neurosci |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6725248/ https://ncbi.nlm.nih.gov/pubmed/16120773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4944-04.2005 |
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