A Novel Positive Allosteric Modulator of the α7 Neuronal Nicotinic Acetylcholine Receptor: In Vitro and In Vivo Characterization

Several lines of evidence suggest a link between the α7 neuronal nicotinic acetylcholine receptor (nAChR) and brain disorders including schizophrenia, Alzheimer's disease, and traumatic brain injury. The present work describes a novel molecule, 1-(5-chloro-2,4-dimethoxy-phenyl)-3-(5-methyl-isox...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hurst, Raymond S., Hajós, Mihaly, Raggenbass, Mario, Wall, Theron M., Higdon, Nicole R., Lawson, Judy A., Rutherford-Root, Karen L., Berkenpas, Mitchell B., Hoffmann, W. E., Piotrowski, David W., Groppi, Vincent E., Allaman, Geraldine, Ogier, Roch, Bertrand, Sonia, Bertrand, Daniel, Arneric, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725110/
https://ncbi.nlm.nih.gov/pubmed/15858066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5269-04.2005
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