Selective Blockade of the Capsaicin Receptor TRPV1 Attenuates Bone Cancer Pain

Cancer colonization of bone leads to the activation of osteoclasts, thereby producing local tissue acidosis and bone resorption. This process may contribute to the generation of both ongoing and movement-evoked pain, resulting from the activation of sensory neurons that detect noxious stimuli (nocic...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ghilardi, Joseph R., Röhrich, Heidi, Lindsay, Theodore H., Sevcik, Molly A., Schwei, Matthew J., Kubota, Kazufumi, Halvorson, Kyle G., Poblete, Jeannie, Chaplan, Sandra R., Dubin, Adrienne E., Carruthers, Nicholas I., Swanson, Devin, Kuskowski, Michael, Flores, Christopher M., Julius, David, Mantyh, Patrick W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725088/
https://ncbi.nlm.nih.gov/pubmed/15788769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3815-04.2005
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