Activation of Early Silent Synapses by Spontaneous Synchronous Network Activity Limits the Range of Neocortical Connections

During the early development of neocortical networks, many glutamatergic synapses lack AMPA receptors and are physiologically silent. We show in neocortical cultures that spontaneous synchronous network activity is able to convert silent synapses to active synapses by the incorporation of AMPA recep...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Voigt, Thomas, Opitz, Thoralf, de Lima, Ana Dolabela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2005
Schlagworte:
Development/Plasticity/Repair
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725027/
https://ncbi.nlm.nih.gov/pubmed/15872108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3803-04.2005
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