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Inhibition of nSMase2 Reduces the Transfer of Oligomeric α-Synuclein Irrespective of Hypoxia

Recently, extracellular vesicles (EVs), such as exosomes, have been proposed to play an influential role in the cell-to-cell spread of neurodegenerative diseases, including the intercellular transmission of α-synuclein (α-syn). However, the regulation of EV biogenesis and its relation to Parkinson’s...

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Bibliografiske detaljer
Udgivet i:Front Mol Neurosci
Main Authors: Sackmann, Valerie, Sinha, Maitrayee Sardar, Sackmann, Christopher, Civitelli, Livia, Bergström, Joakim, Ansell-Schultz, Anna, Hallbeck, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724746/
https://ncbi.nlm.nih.gov/pubmed/31555088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00200
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