Prevalence of the UGT1A1*28 promoter polymorphism and breast cancer risk among African American women in Memphis, TN

Inherited variations in UDP-glucuronosyltransferase 1A1 (UGT1A1) are associated with an increased breast cancer risk in women of African ancestry. The UGT1A1*28 promoter polymorphism is characterized by the presence of 7 TA repeats in the TATA box sequence and results in reduced UGT1A1 gene expressi...

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Publicado en:Cancer Health Disparities
Autores principales: Smith, Alana, Cropp, Cheryl D., Vidal, Gregory, Pritchard, Elizabeth, Cordero, Jennifer, Simpson, Claire, Starlard-Davenport, Athena
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724729/
https://ncbi.nlm.nih.gov/pubmed/31485577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.9777/chd.2019.1015
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