Disrupted placental serotonin synthetic pathway and increased placental serotonin: Potential implications in the pathogenesis of human fetal growth restriction

OBJECTIVES: Placental insufficiency contributes to altered maternal-fetal amino acid transfer, and thereby to poor fetal growth. An important placental function is the uptake of tryptophan and its metabolism to serotonin (5-HT) and kynurenine metabolites, which are essential for fetal development. W...

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Bibliographic Details
Published in:Placenta
Main Authors: Ranzil, Suveena, Ellery, Stacey, Walker, David W., Vaillancourt, Cathy, Alfaidy, Nadia, Bonnin, Alexander, Borg, Anthony, Wallace, Euan M., Ebeling, Peter R., Erwich, Jan Jaap, Murthi, Padma
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724713/
https://ncbi.nlm.nih.gov/pubmed/31176514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2019.05.012
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