Proinflammatory Differentiation of Macrophages Through Microparticles That Form Immune Complexes Leads to T- and B-Cell Activation in Systemic Autoimmune Diseases

Patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) demonstrate increased circulating microparticles (MP). These vesicles, primarily those that form immune complexes (MP-IC), may activate monocytes. We evaluated the effect of MP and MP-IC in the differentiation of monocyte...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Burbano, Catalina, Villar-Vesga, Juan, Vásquez, Gloria, Muñoz-Vahos, Carlos, Rojas, Mauricio, Castaño, Diana
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724570/
https://ncbi.nlm.nih.gov/pubmed/31555283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02058
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