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The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis

P5A ATPases are expressed in the endoplasmic reticulum (ER) of all eukaryotic cells, and their disruption results in severe ER stress. However, the function of these ubiquitous membrane proteins, which belong to the P-type ATPase superfamily, is unknown. We purified a functional tagged version of th...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Sørensen, Danny Mollerup, Holen, Henrik Waldal, Pedersen, Jesper Torbøl, Martens, Helle Juel, Silvestro, Daniele, Stanchev, Lyubomir Dimitrov, Costa, Sara Rute, Günther Pomorski, Thomas, López-Marqués, Rosa Laura, Palmgren, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724510/
https://ncbi.nlm.nih.gov/pubmed/30785834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-06-0365
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