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Enasidenib in acute myeloid leukemia: clinical development and perspectives on treatment

Recently there has been a significant progression in the understanding of molecular mutations driving biochemical and cellular signaling changes leading to survival and proliferation of leukemia cells in patients with acute myeloid leukemia (AML). Preclinical studies have demonstrated a mutated enzy...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Reed, Daniel R, Elsarrag, Ramey Z, Morris, Amy L, Keng, Michael K
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724422/
https://ncbi.nlm.nih.gov/pubmed/31564968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S162784
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