Interferon-α exacerbates neuropsychiatric phenotypes in lupus-prone mice

BACKGROUND: Neuropsychiatric systemic lupus erythaematosus (NP-SLE) is one of the major manifestations of lupus. However, the mechanisms involved in NP-SLE are still largely unknown. The abnormal activation of the type I IFN signalling pathway is involved in SLE pathogenesis and is linked to NP-SLE,...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Zeng, Jing, Meng, Xinyu, Zhou, Ping, Yin, Zhihua, Xie, Qinglian, Zou, Hong, Shen, Nan, Ye, Zhizhong, Tang, Yuanjia
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724270/
https://ncbi.nlm.nih.gov/pubmed/31481114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-019-1985-9
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