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Enrichment of genes associated with squamous differentiation in cancer initiating cells isolated from urothelial cells transformed by the environmental toxicant arsenite

Arsenic is an environmental toxicant with long-term exposure associated with the development of urothelial carcinomas. Our lab has developed an in-vitro model of urothelial carcinoma by exposing the immortal, but non-tumorigenic bladder cell line, the UROtsa, to arsenite (As(3+)). These transformed...

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Publicat a:Toxicol Appl Pharmacol
Autors principals: Hoggarth, Zachary E., Osowski, Danyelle B., Slusser-Nore, Andrea, Shrestha, Swojani, Pathak, Prakash, Solseng, Theoren, Garrett, Scott H., Patel, Divyen H., Savage, Evan, Sens, Donald A, Somji, Seema
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724223/
https://ncbi.nlm.nih.gov/pubmed/31047981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2019.04.021
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