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Transtympanic Delivery of Local Anesthetics for Pain in Acute Otitis Media

Acute otitis media (AOM) commonly causes pain and distress in children. Existing analgesic ototopical drops have limited effectiveness due to the impermeable nature of the tympanic membrane. We developed a local drug delivery system to provide sustained pain relief in patients with AOM, achieved by...

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Détails bibliographiques
Publié dans:Mol Pharm
Auteurs principaux: Yang, Rong, Saarinen, Riitta, Okonkwo, Obiajulu S., Hao, Yi, Mehta, Manisha, Kohane, Daniel S.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724207/
https://ncbi.nlm.nih.gov/pubmed/30840478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b01235
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