Bronchoalveolar Lavage Fluid from COPD Patients Reveals More Compounds Associated with Disease than Matched Plasma

Smoking causes chronic obstructive pulmonary disease (COPD). Though recent studies identified a COPD metabolomic signature in blood, no large studies examine the metabolome in bronchoalveolar lavage (BAL) fluid, a more direct representation of lung cell metabolism. We performed untargeted liquid chr...

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Vydáno v:Metabolites
Hlavní autoři: Halper-Stromberg, Eitan, Gillenwater, Lucas, Cruickshank-Quinn, Charmion, O’Neal, Wanda Kay, Reisdorph, Nichole, Petrache, Irina, Zhuang, Yonghua, Labaki, Wassim W., Curtis, Jeffrey L., Wells, James, Rennard, Stephen, Pratte, Katherine A., Woodruff, Prescott, Stringer, Kathleen A., Kechris, Katerina, Bowler, Russell P.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724137/
https://ncbi.nlm.nih.gov/pubmed/31349744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo9080157
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