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In-Depth Bioinformatic Study of the CLDN16 Gene and Protein: Prediction of Subcellular Localization to Mitochondria

Background and Objectives: The defects in the CLDN16 gene are a cause of primary hypomagnesemia (FHHNC), which is characterized by massive renal magnesium wasting, resulting in nephrocalcinosis and renal failure. The mutations occur throughout the gene’s coding region and can impact on intracellular...

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Détails bibliographiques
Publié dans:Medicina (Kaunas)
Auteurs principaux: Rouka, Erasmia, Liakopoulos, Vassilios, Gourgoulianis, Konstantinos I., Hatzoglou, Chrissi, Zarogiannis, Sotirios G.
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723856/
https://ncbi.nlm.nih.gov/pubmed/31357502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicina55080409
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