Systemic Sclerosis Serum Steers the Differentiation of Adipose-Derived Stem Cells Toward Profibrotic Myofibroblasts: Pathophysiologic Implications

Systemic sclerosis (SSc; scleroderma) is characterized by life-threatening progressive multiorgan fibrosis orchestrated by profibrotic myofibroblasts originating from different sources. Because recent data demonstrated that the majority of myofibroblasts in a murine scleroderma model arise from adip...

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Vydáno v:J Clin Med
Hlavní autoři: Manetti, Mirko, Romano, Eloisa, Rosa, Irene, Fioretto, Bianca Saveria, Praino, Emanuela, Guiducci, Serena, Iannone, Florenzo, Ibba-Manneschi, Lidia, Matucci-Cerinic, Marco
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723717/
https://ncbi.nlm.nih.gov/pubmed/31430950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8081256
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