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Inactivation of Aldehyde Dehydrogenase by Disulfiram in the Presence and Absence of Lipoic Acid or Dihydrolipoic Acid: An in Vitro Study

The inhibition of aldehyde dehydrogenase (ALDH) by disulfiram (DSF) in vitro can be prevented and/or reversed by dithiothreitol (DTT), which is a well-known low molecular weight non-physiological redox reagent commonly used in laboratory experiments. These observations inspired us to ask the questio...

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Vydáno v:Biomolecules
Hlavní autoři: Bilska-Wilkosz, Anna, Górny, Magdalena, Iciek, Małgorzata
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723463/
https://ncbi.nlm.nih.gov/pubmed/31426424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9080375
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