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Doxycycline-Eluting Core-Shell Type Nanofiber-Covered Trachea Stent for Inhibition of Cellular Metalloproteinase and Its Related Fibrotic Stenosis

In this study, we fabricated a doxycycline (doxy)-eluting nanofiber-covered endotracheal stent for the prevention of stent intubation-related tissue fibrosis and re-stenosis. The nanofiber was deposited directly on the outer surface of the stent using a coaxial electrospinning method to form a doxy-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Baskaran, Rengarajan, Ko, Un-Jeong, Davaa, Enkhzaya, Park, Ji Eun, Jiang, Yixin, Lee, Junghan, Yang, Su-Geun
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723391/
https://ncbi.nlm.nih.gov/pubmed/31430987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11080421
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