Correlation between Thiopurine S-Methyltransferase Genotype and Adverse Events in Inflammatory Bowel Disease Patients

Background and Objectives: In patients with inflammatory bowel diseases (IBD), the use of azathioprine results in adverse events at a rate of 5% to 20%. The aim of the study was to assess a possible correlation between genetic variability of the enzyme thiopurine S-methyltransferase (TPMT) and the d...

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Dades bibliogràfiques
Publicat a:Medicina (Kaunas)
Autors principals: Ribaldone, Davide Giuseppe, Adriani, Alessandro, Caviglia, Gian Paolo, De Nicolò, Amedeo, Agnesod, Danilo, Simiele, Marco, Riganò, Danila, Pellicano, Rinaldo, Canaparo, Roberto, Di Perri, Giovanni, D’Avolio, Antonio, Luzza, Francesco, Abenavoli, Ludovico, Saracco, Giorgio Maria, Astegiano, Marco
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723288/
https://ncbi.nlm.nih.gov/pubmed/31387318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicina55080441
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