Correlation between Thiopurine S-Methyltransferase Genotype and Adverse Events in Inflammatory Bowel Disease Patients

Background and Objectives: In patients with inflammatory bowel diseases (IBD), the use of azathioprine results in adverse events at a rate of 5% to 20%. The aim of the study was to assess a possible correlation between genetic variability of the enzyme thiopurine S-methyltransferase (TPMT) and the d...

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Detalhes bibliográficos
Publicado no:Medicina (Kaunas)
Main Authors: Ribaldone, Davide Giuseppe, Adriani, Alessandro, Caviglia, Gian Paolo, De Nicolò, Amedeo, Agnesod, Danilo, Simiele, Marco, Riganò, Danila, Pellicano, Rinaldo, Canaparo, Roberto, Di Perri, Giovanni, D’Avolio, Antonio, Luzza, Francesco, Abenavoli, Ludovico, Saracco, Giorgio Maria, Astegiano, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723288/
https://ncbi.nlm.nih.gov/pubmed/31387318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicina55080441
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