Reprogramming of Urine-Derived Renal Epithelial Cells into iPSCs Using srRNA and Consecutive Differentiation into Beating Cardiomyocytes

The generation of induced pluripotent stem cells (iPSCs) from patient’s somatic cells and the subsequent differentiation into desired cell types opens up numerous possibilities in regenerative medicine and tissue engineering. Adult cardiomyocytes have limited self-renewal capacity; thus, the efficie...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Steinle, Heidrun, Weber, Marbod, Behring, Andreas, Mau-Holzmann, Ulrike, von Ohle, Christiane, Popov, Aron-Frederik, Schlensak, Christian, Wendel, Hans Peter, Avci-Adali, Meltem
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723182/
https://ncbi.nlm.nih.gov/pubmed/31476669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.07.016
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