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Multi-Modulation of Doxorubicin Resistance in Breast Cancer Cells by Poly(l-histidine)-Based Multifunctional Micelles

Even though the reversal of multi-drug resistance (MDR) by numerous nanoparticles has been extensively studied, limited success has been achieved. To overcome this barrier, we report a rationally-designed pH-sensitive micelle, in which doxorubicin (Dox) and resveratrol (Res) were co-loaded. The mice...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Jia, Li, Jia, Nan, Gao, Yan, Hu, Haiyang, Zhao, Xiuli, Chen, Dawei, Qiao, Mingxi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723117/
https://ncbi.nlm.nih.gov/pubmed/31382390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11080385
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