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Structural Variants as a Basis for Targeted Therapies in Hematological Malignancies

Structural variants (SV) are changes in the genomic landscape that can alter gene expression levels and thus lead to disease development. The most common and best studied SVs in hematological malignancies are chromosomal translocations. Here, parts of two genes that are normally on different chromos...

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Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Schütte, Judith, Reusch, Julia, Khandanpour, Cyrus, Eisfeld, Christine
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722867/
https://ncbi.nlm.nih.gov/pubmed/31555592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00839
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