Benzimidazole inhibitors of the major cysteine protease of Trypanosoma brucei

AIM: Limitations in available therapies for trypanosomiases indicate the need for improved medicines. Cysteine proteases cruzain and rhodesain are validated targets for treatment of Chagas disease and human African trypanosomiasis. Previous studies reported a benzimidazole series as potent cruzain i...

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Detaylı Bibliyografya
Yayımlandı:Future Med Chem
Asıl Yazarlar: Pereira, Glaécia AN, Santos, Lucianna H, Wang, Steven C, Martins, Luan C, Villela, Filipe S, Liao, Weiting, Dessoy, Marco A, Dias, Luiz C, Andricopulo, Adriano D, Costa, Mariana AF, Nagem, Ronaldo AP, Caffrey, Conor R, Liedl, Klaus R, Caffarena, Ernesto R, Ferreira, Rafaela S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Newlands Press Ltd 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722484/
https://ncbi.nlm.nih.gov/pubmed/31469332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0523
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