Benzimidazole inhibitors of the major cysteine protease of Trypanosoma brucei

AIM: Limitations in available therapies for trypanosomiases indicate the need for improved medicines. Cysteine proteases cruzain and rhodesain are validated targets for treatment of Chagas disease and human African trypanosomiasis. Previous studies reported a benzimidazole series as potent cruzain i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Future Med Chem
मुख्य लेखकों: Pereira, Glaécia AN, Santos, Lucianna H, Wang, Steven C, Martins, Luan C, Villela, Filipe S, Liao, Weiting, Dessoy, Marco A, Dias, Luiz C, Andricopulo, Adriano D, Costa, Mariana AF, Nagem, Ronaldo AP, Caffrey, Conor R, Liedl, Klaus R, Caffarena, Ernesto R, Ferreira, Rafaela S
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Newlands Press Ltd 2019
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722484/
https://ncbi.nlm.nih.gov/pubmed/31469332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0523
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