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Benzimidazole inhibitors of the major cysteine protease of Trypanosoma brucei
AIM: Limitations in available therapies for trypanosomiases indicate the need for improved medicines. Cysteine proteases cruzain and rhodesain are validated targets for treatment of Chagas disease and human African trypanosomiasis. Previous studies reported a benzimidazole series as potent cruzain i...
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| Publié dans: | Future Med Chem |
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| Auteurs principaux: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Newlands Press Ltd
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6722484/ https://ncbi.nlm.nih.gov/pubmed/31469332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0523 |
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