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Suppression of CD81 promotes bladder cancer cell invasion through increased matrix metalloproteinase expression via extracellular signal-regulated kinase phosphorylation

PURPOSE: CD81 is a prognostic biomarker for high-grade bladder cancer (BC). In this study, we aimed to determine the functional mechanisms underlying the role of CD81 in BC progression. MATERIALS AND METHODS: In two invasive BC cell lines (T24, J82), CD81 expression was suppressed by the transfectio...

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Vydáno v:Investig Clin Urol
Hlavní autoři: Park, Hyun Sik, Lee, Suhyuk, Lee, Jisu, Shin, Hyun Bin, Yoo, Seung-Min, Lee, Myung-Shin, Park, Jinsung
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Urological Association 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722400/
https://ncbi.nlm.nih.gov/pubmed/31501803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4111/icu.2019.60.5.396
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