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The significant cost of systematic reviews and meta-analyses: A call for greater involvement of machine learning to assess the promise of clinical trials

BACKGROUND: More than 90% of clinical-trial compounds fail to demonstrate sufficient efficacy and safety. To help alleviate this issue, systematic literature review and meta-analysis (SLR), which synthesize current evidence for a research question, can be applied to preclinical evidence to identify...

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Dades bibliogràfiques
Publicat a:Contemp Clin Trials Commun
Autors principals: Michelson, Matthew, Reuter, Katja
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722281/
https://ncbi.nlm.nih.gov/pubmed/31497675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2019.100443
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