Downregulation of IL-18 Expression in the Gut by Metformin-induced Gut Microbiota Modulation

IL-18 is a crucial pro-inflammatory cytokine that mediates chronic intestinal inflammation. Metformin, an anti-diabetic drug, was reported to have ameliorative effects on inflammatory bowel disease. Recently, the mechanism of action of metformin was explained as a modulation of gut microbiota. In th...

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Vydáno v:Immune Netw
Hlavní autoři: Lee, Heetae, Kim, Jiyeon, An, Jinho, Lee, Sungwon, Choi, Dohyun, Kong, Hyunseok, Song, Youngcheon, Park, Il Ho, Lee, Chong-Kil, Kim, Kyungjae
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Association of Immunologists 2019
Témata:
Brief Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722274/
https://ncbi.nlm.nih.gov/pubmed/31501716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2019.19.e28
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