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A “human knockout” model to investigate the influence of the α-actinin-3 protein on exercise-induced mitochondrial adaptations
Research in α-actinin-3 knockout mice suggests a novel role for α-actinin-3 as a mediator of cell signalling. We took advantage of naturally-occurring human “knockouts” (lacking α-actinin-3 protein) to investigate the consequences of α-actinin-3 deficiency on exercise-induced changes in mitochondria...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6722100/ https://ncbi.nlm.nih.gov/pubmed/31481717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49042-y |
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