Alcohol effects on colon epithelium are time dependent

BACKGROUND: Alcohol intake increases the risk of developing colon cancer. Circadian disruption promotes alcohol’s effect on colon carcinogenesis through unknown mechanisms. Alcohol’s metabolites induce DNA damage, an early step in carcinogenesis. We assessed the effect of time of alcohol consumption...

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Udgivet i:Alcohol Clin Exp Res
Main Authors: Bishehsari, Faraz, Zhang, Lijuan, Voigt, Robin M., Maltby, Natalie, Semsarieh, Bita, Zorub, Eyas, Shaikh, Maliha, Wilber, Sherry, Armstrong, Andrew R, Mirbagheri, Seyed Sina, Preite, Nailliw Z., Song, Peter, Stornetta, Alessia, Balbo, Silvia, Forsyth, Christopher B., Keshavarzian, Ali
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722020/
https://ncbi.nlm.nih.gov/pubmed/31237690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14141
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