Complex Interplay Among Nuclear Receptor Ligands, Cytosine Methylation, and the Metabolome in Driving Tris(1,3-Dichloro-2-Propyl) Phosphate-Induced Epiboly Defects in Zebrafish

Tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) is a high-production volume organophosphate flame retardant (OPFR) that induces epiboly defects during zebrafish embryogenesis, leading to disruption of dorsoventral patterning. Therefore, the objectives of this study were to 1) identify potential mecha...

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Veröffentlicht in:Environ Sci Technol
Hauptverfasser: Dasgupta, Subham, Vliet, Sara M. F., Cheng, Vanessa, Mitchell, Constance A., Kirkwood, Jay, Vollaro, Alyssa, Hur, Manhoi, Mehdizadeh, Chris, Volz, David C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721996/
https://ncbi.nlm.nih.gov/pubmed/31385694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.est.9b04127
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