Phosphorylation of Merlin by Aurora A kinase appears necessary for mitotic progression

Although Merlin's function as a tumor suppressor and regulator of mitogenic signaling networks such as the Ras/rac, Akt, and Hippo pathways is well-documented, in mammals as well as in insects, its role during cell cycle progression remains unclear. In this study, using a combination of approac...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Mandati, Vinay, Del Maestro, Laurence, Dingli, Florent, Lombard, Bérangère, Loew, Damarys, Molinie, Nicolas, Romero, Stephane, Bouvard, Daniel, Louvard, Daniel, Gautreau, Alexis M., Pasmant, Eric, Lallemand, Dominique
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721933/
https://ncbi.nlm.nih.gov/pubmed/31296571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006937
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