Physioxia Has a Beneficial Effect on Cartilage Matrix Production in Interleukin-1 Beta-Inhibited Mesenchymal Stem Cell Chondrogenesis

Osteoarthritis (OA) is a degenerative condition that involves the production of inflammatory cytokines (e.g., interleukin-1β (IL-1β), tumour necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6)) that stimulate degradative enzymes, matrix metalloproteinases (MMPs) and aggrecanases (ADAMTS) resultin...

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Bibliographic Details
Published in:Cells
Main Authors: Pattappa, Girish, Schewior, Ruth, Hofmeister, Isabelle, Seja, Jennifer, Zellner, Johannes, Johnstone, Brian, Docheva, Denitsa, Angele, Peter
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721827/
https://ncbi.nlm.nih.gov/pubmed/31434236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080936
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